International Journal of Ophthalmology & Vision Research

E-ISSN: 2640-5660
Pubmed NLM Abbr: Int J Ophthal Vision Res
Journal Full Title: International Journal of Ophthalmology & Vision Research
Website: Click here
DOI: 10.37871 (CrossRef)
Review Process type: Double Blind
Publication fee: Click here
Plagiarism checker: iThenticate
Language: English
Ability to collect research papers: Worldwide
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License: Creative Commons License Open Access by International Journal of Ophthalmology & Vision Research is licensed under a Creative Commons Attribution 4.0 International License. Based on a work at SciRes Literature..

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Research Articles

Public Awareness and Knowledge of Factors Associated with Myopia in Kisumu County, Western Kenya 01/30/2021

Study of Kenyan Optometrists View on Future of Optometry and Prospective Impact on Public Health 01/04/2021

Selective Laser Trabeculoplasty 1 and 2 Year Pressure Reduction 03/08/2019

Color Vision in Normal Myopic Eyes and Changes before and after Laser in Situ Keratomileusis 11/19/2018

Virucidal Activity of Hand Sanitizer against Ocular Isolates of Adenovirus 09/17/2018

Review Articles

Ocular Manifestations of Charcot-Marie-Tooth Disease: A Short Review 12/27/2019

A Growing Research Area of In vitro Cell Culture Technologies for Corneal Surface Regeneration: A Short Communication of Basic Steps to Cultivate Limbal Epithelial Stem Cells 02/22/2018

Practical Guide for Premium IOLs in 2017 04/18/2017

Articles

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Hanna Balakier, CReATe Fertility Centre, Toronto, ON, Canada

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International Journal of Neurological Disorders

Meysoon Adil Abdelrahman Elagib

Senior Resident of Internal Medicine, Khartoum, Sudan

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International Journal of Virology & Infectious Diseases

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Christian-Albrechts University, Germany

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Interrnist-Endocrinologist at Naafs International Health Consultancy, The Netherlands

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University of Florence, Italy

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Christophe P Ribelayga

University of Texas Health Science Center at Houston , USA

Christophe P. Ribelayga research aims to understand how we see during the day and night. Our visual system is remarkable in that it can operate under the bright midday sun, at night under starlight, and at all times in between when ambient light intensity varies by more than 10 billion fold. The mechanisms responsible for this remarkable adaptation are known to primarily originate in the eye and more specifically in its sensory part, the retina. Adaptation to the daily changes in ambient light intensity in the retina depends on a specific functional architecture, including 2 types of photoreceptors, rods and cones, and a wide variety of neuronal mechanisms encompassing both adaptive mechanisms driven by ambient light and endogenous mechanisms, such as circadian clocks. The main property of circadian clocks is that they are self-sustained in nature, and therefore they function even in the absence of time cues, such as in constant conditions (i.e. constant darkness) with a period of approximately 24 h, hence the term circadian (from the Latin circa dies, which translates into “about one day”). Circadian clocks in the retina keep track of the highly predictable daily changes in the ambient light intensity, thus helping the retina to anticipate the abrupt changes in lighting conditions at transition times (i.e. dawn and dusk) and optimize retinal processing for high-acuity low-sensitivity daytime vision or low-acuity high-sensitivity nighttime vision. Genetic dysfunction of the retinal clocks or of circadian signaling in the retina produces marked deficits in retinal responses to light and compromises retinal cell viability. Thus, functional circadian clocks are essential for normal maintenance and function of the retina.

Our long-term goal is to understand how circadian clocks in the retina modulate retinal function on a daily basis, and why clock malfunction impinges on information processing and cell viability. We expect that our work will bring us closer to fully understand why circadian timing is so critical in the retina. We also expect that understanding how circadian clocks control neuronal activity and functional pathways in the retina will be of great benefit towards our understanding of the general rules governing circadian clock function and neuroplasticity in the central nervous system.