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Minervini Crescenzio Francesco

Minervini Crescenzio Francesco

Università degli Studi di Bari “Aldo Moro”, Italy

During my PhD I have conduct studies to evaluate the insulator properties of some regions of transposable elements in Drosophila melanogaster. These properties I have proved were conserved in human cells and were used for the construction of expression vectors to be used in gene therapy that has been patented.
At the McGowan institute of the University of Pittsburgh (USA), I carried out studies on amniotic epithelial cells extracted directly from the placenta in order to assess whether their use in the generation of IPs (induced pluripotent) cells could offer a better performance in cellular reprogramming.
Since I was employed at the Laboratory of "Hematological Sciences" of the University of Bari (Italy) in 2009 I was focused genomics and transcriptomics of hematological malignances with the aim to discover diagnostic and prognostic markers and develop new tests.
Recently I have oriented my attention on the development of diagnostic tests (protocols and
2
analysis pipelines) using nanopore sequencing technology..Biography:
During my PhD I have conduct studies to evaluate the insulator properties of some regions of transposable elements in Drosophila melanogaster. These properties I have proved were conserved in human cells and were used for the construction of expression vectors to be used in gene therapy that has been patented.
At the McGowan institute of the University of Pittsburgh (USA), I carried out studies on amniotic epithelial cells extracted directly from the placenta in order to assess whether their use in the generation of IPs (induced pluripotent) cells could offer a better performance in cellular reprogramming.
Since I was employed at the Laboratory of "Hematological Sciences" of the University of Bari (Italy) in 2009 I was focused genomics and transcriptomics of hematological malignances with the aim to discover diagnostic and prognostic markers and develop new tests.
Recently I have oriented my attention on the development of diagnostic tests (protocols and
2
analysis pipelines) using nanopore sequencing technology.
Research Interest:

Molecular biology, genetics, cancer research, hematological malignancies, NGS

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